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Bendit Bendamustine Injection Natco Pharma

Medicine Detail

Brand Name: Bendit

Contents: Bendamustine hydrochloride

Strength: 100 mg

Form: Lyophilized powder in vial 

Manufacturer: Natco Pharma Limited


Bendit Bendamustine ( Generic Treanda ) is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. It is classified as an alkylating agent. Alkylating agents are most active in the resting phase of the cell-cycle. It is a nitrogen mustard derivative and is active against resting as well as dividing cells.


Bendamustine is used for treatment of
chronic lymphocyticleukemia (CLL) i.e. cancer of white blood cells in bone marrow. It is also used for the treatment of patients with indolent B-cell non-Hodgkin's lymphoma.

It works by destroying the DNA, thus killing the existing cancer cells and also preventing the growth and spread of new cancer cells.


Consult your Doctor if you suffer from these side effects:

·         Fever, cough, mouth sores; nausea, vomiting, diarrhea, constipation; a headache, tiredness, dizziness, drowsiness; swelling in your hands or feet; loss of appetite, weight loss; or mild skin rash.

·         Severe ongoing nausea, Vomiting, or diarrhea; Feeling very weak or tired; a cough with yellow or green mucus, Stabbing chest pain, Wheezing, Feeling short of breath; Pain, swelling, Redness, Skin changes or signs of infection where the medicine was injected.

·         Low blood cell counts--fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed.

·         Signs of tumor cell breakdown--lower back pain, blood in your urine, little or no urination; numbness or tingly feeling around your mouth; muscle weakness or tightness; fast or slow heart rate, weak pulse, confusion, fainting.

·         Dehydrations symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

·         Low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling.

·         Severe skin reaction--swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Bendit Bendamustine Injection Precautions:


·         Before using Bendamustine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as mannitol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

·         Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood/bone marrow disorders, kidney problems, liver problems, recent/current infection.

·         Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

·         This drug may make you dizzy or cause tiredness. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

·         This drug is not recommended for use during pregnancy. It may harm an unborn baby. It is important to prevent pregnancy while using this medication and for 3 months after treatment. If you become pregnant or think you may be pregnant, or if your partner becomes pregnant, tell your doctor right away.

·         It is not known whether this drug passes into breast milk. However, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

This is not a complete list. Ask your health care provider for more information.


Store intact vials between 2°C to 8°C (36°F to 46°F); protect from light.



Tell your doctor about all your current medicines and any you start or stop using, especially:
This document does not contain all possible interactions. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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