What is Selumetinib?

Selumetinib is a precision medicine used for treating pediatric patients with Neurofibromatosis Type 1 (NF1) who have symptomatic, inoperable plexiform neurofibromas. NF1 is a genetic condition that can cause tumors to grow along nerves, leading to complications such as pain, deformity, and nerve dysfunction.

Selumetinib works by inhibiting MEK1/2 proteins, which are part of the signaling pathway responsible for tumor growth in NF1.

Available Strengths

• Selumetinib 10mg Capsules
• Selumetinib 25mg Capsules

These strengths provide flexibility for personalized dosing based on the patient’s weight and condition.

Common Side Effects

As with any targeted cancer therapy, Selumetinib may cause side effects, including:

• Nausea and vomiting
• Diarrhea
• Fatigue
• Skin rash
• Increased liver enzymes
• Muscle or joint pain

Regular monitoring by your healthcare provider will help manage these effects.

Key Benefits

Targeted Therapy: Directly blocks the pathways driving tumor growth in NF1.
Proven in Clinical Trials: Shown to shrink tumors and improve quality of life in pediatric NF1 patients.
Oral Medication: Easy-to-administer capsule format for at-home treatment.
First FDA-Approved Treatment for NF1: Provides new hope for patients and families dealing with complex neurofibromas.

Disclaimer

RxLane provides information for educational purposes only. All trademarks, brands, and service marks are the property of their respective owners. RxLane does not offer medical advice. Please consult your doctor for appropriate diagnosis and treatment. This content is intended for wholesalers, doctors, hospitals, clinics, pharmacies, and medical institutions.