ABOUT BENDIT 

Bendit is an anti-cancer (“antineoplastic” or
“cytotoxic”) chemotherapy drug. It is classified as an alkylating
agent. Alkylating agents are most active in the resting phase of the
cell-cycle. It is a nitrogen mustard derivative and is active against resting
as well as dividing cells.

BENDIT USES:

Bendamustine is used for treatment of chronic lymphocytic
leukemia (CLL) i.e. cancer of white blood cells in bone marrow. It is also used
for the treatment of patients with indolent B-cell non-Hodgkin’s lymphoma.

It works by
destroying the DNA, thus killing the existing cancer cells and also preventing
the growth and spread of new cancer cells.

BENDAMUSTINE SIDE
EFFECTS:

Consult your Doctor if you suffer from these side effects:

·        
Fever, cough, mouth
sores; nausea, vomiting, diarrhea, constipation; a headache, tiredness,
dizziness, drowsiness; swelling in your hands or feet; loss of appetite, weight
loss; or mild skin rash.

·        
Severe ongoing
nausea, Vomiting, or diarrhea; Feeling very weak or tired; a cough with yellow
or green mucus, Stabbing chest pain, Wheezing, Feeling short of breath; Pain,
swelling, Redness, Skin changes or signs of infection where the medicine was
injected.

·        
Low blood cell
counts–fever, chills, flu-like symptoms, swollen gums, mouth sores, skin
sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling
light-headed.

·        
Signs of tumor cell
breakdown–lower back pain, blood in your urine, little or no urination;
numbness or tingly feeling around your mouth; muscle weakness or tightness;
fast or slow heart rate, weak pulse, confusion, fainting.

·        
Dehydrations
symptoms–feeling very thirsty or hot, being unable to urinate, heavy sweating,
or hot and dry skin.

·        
Low potassium–leg
cramps, constipation, irregular heartbeats, fluttering in your chest, extreme
thirst, increased urination, numbness or tingling, muscle weakness or limp
feeling.

·        
Severe skin reaction–swelling
in your face or tongue, burning in your eyes, skin pain followed by a red or
purple skin rash that spreads (especially in the face or upper body) and causes
blistering and peeling.

Bendit Bendamustine
Injection Precautions:

 

·        
Before using
Bendamustine, tell your doctor or pharmacist if you are allergic to it; or if
you have any other allergies. This product may contain inactive ingredients
(such as mannitol), which can cause allergic reactions or other problems. Talk
to your pharmacist for more details.

·        
Before using this
medication, tell your doctor or pharmacist your medical history, especially of:
blood/bone marrow disorders, kidney problems, liver problems, recent/current
infection.

·        
Do not have
immunizations/vaccinations without the consent of your doctor. Avoid contact
with people who have recently received live vaccines (such as flu vaccine
inhaled through the nose).

·        
This drug may make
you dizzy or cause tiredness. Do not drive, use machinery, or do any activity
that requires alertness or clear vision until you are sure you can perform such
activities safely. Limit alcoholic beverages.

·        
This drug is not
recommended for use during pregnancy. It may harm an unborn baby. It is
important to prevent pregnancy while using this medication and for 3 months
after treatment. If you become pregnant or think you may be pregnant, or if
your partner becomes pregnant, tell your doctor right away.

·        
It is not known
whether this drug passes into breast milk. However, breast-feeding while using
this drug is not recommended. Consult your doctor before breast-feeding.

This is not a complete list. Ask your health care provider
for more information.

STORAGE
REQUIREMENTS:

Store intact vials between 2°C to 8°C (36°F to 46°F); protect
from light.

 

DRUG
INTERACTIONS:

Tell your doctor about all your current medicines and any you
start or stop using, especially:
    Allopurinol;
    Ciprofloxacin;
    Fluvoxamine;
    Lansoprazole;
    Omeprazole.
This document does not contain all possible interactions.
Keep a list of all your medications with you, and share the list with your
doctor and pharmacist.

WHAT
IS BIMODE TABLETS?

Bendamustine is an
anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy
drug. Bendamustine is classified as an “alkylating agent. Bendamustine is
classified as an alkylating agent.  Alkylating agents are most active in
the resting phase of the cell-cycle.  There are several types of
alkylating agents. Bendamustine is a nitrogen mustard derivative and is active against
resting as well as dividing cells.

USES OF BIMODE TABLETS:

Bimode Injection is
used for Acute lymphocytic leukaemia, Chronic lymphocytic
leukemia, Non-hodgkin’s lymphomaand other conditions. Bimode Injection may
also be used for purposes not listed in this medication guide.

It is used widely in the treatments of
chronic lymphatic leukemia, non Hodgkin lymphoma, and myeloma. It
is included in World Health Organization’s list of Essential Medicines. It’s
often used as a sole medicine for the treatment of above mentioned conditioned,
or sometimes combinatively with other medications. No tablets or pills are
available of this medication. Bimode 100Mg Injection works by interfering into
the cancerous cells and hence the cells can’t divide into two and prevent
further spread.

POSSIBLE
SIDE EFFECTS:

This is
a strong drug and include various side effects if administered improperly hence
doctors supervision is impeccable. Side effects like low blood count, nausea,
vomiting, fatigue, diarrhea, skin problems, renal problems may be encountered
after administration of Bimode 100Mg Injection. In rare cases infertility and other
similar problems may be seen.

Some people receiving a bendamustine injection have had a reaction to the
infusion (when the medicine is injected into the vein). Tell your caregiver
right away if you have fever chills, itching, or skin rash during or shortly
after the injection.
When symptoms like extreme nausea, vomiting,
or unusual bleeding, blood in urine or stool may show up
its time to contact the doctor as soon as possible. But when administered under
extreme guidance this drug works well in treating the above mentioned
conditioned.

COMMON SIDE EFFECTS MAY
INCLUDE:

The most commonly
reported side-effects of Bimode Injection are nausea, vomiting,
fatigue, diarrhea, constipation, and fever.
 
severe ongoing nausea, vomiting, or diarrhea; feeling very weak or tired; cough
with yellow or green mucus, stabbing chest pain, wheezing, feeling short of
breath; pain, swelling, redness, skin changes, or signs of infection where the
medicine was injected;
low blood cell counts–fever, chills, flu-like symptoms, swollen gums, mouth
sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual
bleeding, feeling light-headed;

signs of tumor cell breakdown–lower back pain, blood in your urine, little or
no urination; numbness or tingly feeling around your mouth; muscle weakness or
tightness; fast or slow heart rate, weak pulse, confusion, fainting;

dehydration symptoms–feeling very thirsty or hot, being unable to urinate,
heavy sweating, or hot and dry skin;
low potassium–leg cramps, constipation, irregular heartbeats, fluttering in
your chest, extreme thirst, increased urination, numbness or tingling, muscle
weakness or limp feeling; or

severe skin reaction–swelling in your face or tongue, burning in your eyes,
skin pain followed by a red or purple skin rash that spreads (especially in the
face or upper body) and causes blistering and peeling.

 

DRUGS PRECAUTIONS:

Before using Bimode
Injection, inform your doctor about your current list of medications, over the
counter products (e.g. vitamins, herbal supplements, etc.), allergies,
pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming
surgery, etc.). Some health conditions may make you more susceptible to the
side-effects of the drug. Take as directed by your doctor or follow the
direction printed on the product insert. Dosage is based on your condition.
Tell your doctor if your condition persists or worsens.

Bimode 100 mg Injection is
an anti-cancer medication. It works by damaging the genetic material (DNA and
RNA) of the cancer cells. This stops their growth and multiplication.

DRUGS INTERACTIONS:

Monitoring of the blood cell count and potassium level is
required before the start and regularly during the therapy.

Consult your doctor if you have any signs of infection,
fever, lung symptoms, skin reactions, pain in abdomen, blood in urine, reduced
volume of urine.

Inform your doctor if you have heart disease (heart
attack, chest pain, severely disturbed heart rhythms).

Men should adopt appropriate contraceptive measure during
and up to 6 months after treatment and may require sperm conservation prior to
treatment because of possibility of irreversible infertility.

Bendamustine may cause sleepiness and dizziness or lack
of coordination; it is advisable to avoid driving or operating heavy machinery
under such circumstances. 

Bendamustine
is not recommended for children and adolescents